From January 1984 to June 1990, 188 patients have undergone cardiac valve replacement (114 MVR, 27 AVR, 47 Multiple valve replacement) wiht the St. Jude Medical prosthesis.
The early mortality rate -A as 6.9%. The most common cause of early death was low out-put syndrome. There were no cases of valve-related early death.
The risk factors for early death were advanced preoperative NYHA functional class (> N), and prolonged ECC and ACC time.
The 175 early survivors were followed-up for a total 372.7 patient-year over a period of 2 to 74 months (Mean SD : 25.618.6 months). During follow up, 12 patient died and late mortality rate was 6.9%.
There were three valve-related late deaths : two were due to valve thrombosis and one was due to hemorrhage. Most late deaths (58%, 7 /12) were from cardiac non-valvular causes.
Valve-related complications occurred at a linearized rate of 3.5% /pt-yr.
Embolism occurred at a rate of 0.85,ol /pt-yr. There were three cases of valve thrombosis (0.8%/pt-yr : two fatal). Hemorrhage due to anticoagulant occurred in 5 patients and a rate of 1.3% pt-yr(one fatal).
Five-year actuarial survival rate was 86.55.1% and 97% of patient were in NYHA functional class I or II at three months postoperatively.
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